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Nintendo DS "D" Games
- Danny Phantom: Urban Jungle
- Deal or No Deal
- Death Jr. and the Science Fair of Doom
- Deep Labyrinth
- Dementium: The Ward
- Di-Gata Defenders
- Diddy Kong Racing DS
- Dig Dug: Digging Strike
- Digimon World Dawn
- Digimon World DS
- Digimon World Dusk
- Diner Dash
- Dino Master: Dig, Discover, Duel
- Dinosaur King
- Disney Animated
- Disney Cory in the House
- Disney Friends
- Disney Princess: Magical Jewels
- Disney's Chicken Little: Ace in Action
- Disney's Kim Possible: Global Gemini
- Disney's Kim Possible: Kimmunicator
- Disney's Meet the Robinsons
- DK: Jungle Climber
- Dogz
- Don King Presents: Prizefighter
- Dora the Explorer: Dora Saves the Mermaids
- Draglade
- Dragon Ball Z: Harukanaru Densetsu
- Dragon Ball Z: Supersonic Warriors 2
- Dragon Booster
- Dragon Quest Heroes: Rocket Slime
- Dragon Quest Monsters: Joker
- Drake & Josh: Talent Showdown
- Drawn to Life
- Dream Pinball 3D
- Drone Tactics
- Ducati Moto
- Dungeon Explorer: Warrior of Ancient Arts
- Dynasty Warriors DS
- Dynasty Warriors DS: Fighter's Battle